Rubella seroprevalence in an unvaccinated pregnant population in Malatya, Turkey.

نویسندگان

  • E Pehlivan
  • L Karaoglu
  • M Ozen
  • G Gunes
  • M S Tekerekoglu
  • M F Genc
  • M Egri
  • C Ercan
چکیده

BACKGROUND Controlling congenital rubella by 2010 is one of the targets of the World Health Organization. Most European countries currently include rubella vaccine in their national immunization programmes, but not yet in Turkey. OBJECTIVES To define rubella seroprevalence in pregnancy in Malatya, Turkey. STUDY DESIGN A cross-sectional interview survey was conducted among pregnant women living in Malatya province from November 2003 to May 2004, together with a follow-up component. METHODS Stratified probability proportional to size sampling methodology. A total of 824 pregnant women from 60 clusters were enrolled. After obtaining informed consent, participants' socio-demographic and fertility characteristics were collected by interview questionnaire. Various blood samples were drawn. After storing serum samples at -20 degrees C for 6 months, anti-rubella IgM and IgG titres were studied by micro ELISA. Only 803 sera were eligible for serological study. RESULTS Of the 803 samples tested for rubella antibodies, 753 cases (93.8%) had anti-rubella IgG positivity, indicating past infection. Five of the pregnant women (0.6%) had both anti-rubella IgM and IgG positive results, suggesting a recent infection. The remaining 45 women (5.6%) were seronegative for both antibodies. Seroprevalence was not associated with age or urban/rural residency. All the five anti-rubella IgM positive women were in the second trimester of pregnancy. CONCLUSIONS As 5.6% of pregnant women were susceptible to rubella during pregnancy, and five of them had already had a recent infection, immunization efforts should be directed at babies and adolescents.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Age specific rubella seroprevalence of an unvaccinated population of adolescents in Ankara, Turkey.

This study was designed to detect the age-specific rubella seroprevalence of an unvaccinated population of adolescents in Ankara, Turkey. Four hundred and forty adolescents (227 females, 213 males), aged 9-16 years, who were admitted to the Adolescent Unit from July to August 2000 were included in this study. For each participant, a questionnaire was completed and rubella-specific IgG antibodie...

متن کامل

Age-specific mumps seroprevalence of an unvaccinated population of adolescents in Ankara, Turkey.

This study aimed to detect the age-specific mumps seroprevalence of an unvaccinated population of adolescents in Ankara, Turkey and to compare the prevaccination epidemiology of mumps with those of some other countries. Four hundred and forty adolescents (227 females, 213 males) aged 9 - 16 years who were admitted to the Adolescent Unit were included in this study. For each participant, a quest...

متن کامل

Age-specific rubella seroprevalence in unvaccinated adolescents in Ankara, Turkey.

The purpose of this study was to determine the age-specific rubella seroprevalence and factors associated with rubella seropositivity in unvaccinated adolescents in Ankara, Turkey. In this cross-sectional study 229 students were selected with stratified sampling methods in 2 primary and 2 high schools of low to medium socioeconomic status. Overall rubella seroprevalence was 92.6%. There was a s...

متن کامل

Rubella seroprevalence among Turkish adolescent girls living in Edirne, Turkey.

This study was designed to estimate the rubella seroprevalence in unvaccinated Turkish adolescent girls in urban and rural areas of Edirne, and to create preventive strategies for congenital rubella syndrome (CRS). The sample, representing 12- to 17-year-old adolescent girls, consisted of 1,600 subjects selected from school lists by systematic and random sampling, which was matched by age and u...

متن کامل

Rubella seroprevalence among first-grade primary school students in a district in Istanbul, Turkey.

OBJECTIVES Rubella vaccination is not included in the national immunization programme of Turkey. However, it is on the market and is recommended, mainly by the private sector, at the age of 12-15 months. Introduction of the rubella vaccine without achieving high coverage has the risk of shifting the mean age of rubella infection among the unvaccinated population to reproductive ages. The aim of...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • Public health

دوره 121 6  شماره 

صفحات  -

تاریخ انتشار 2007